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- A study of the effect of cyclosporine on fevipiprant pharmacokinetics and its absolute bioavailability using an intravenous microdose approach
- Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate 快喵Ⅴpn Tools and Clearance Prediction
- Organic cation transporter 1 and 3 contribute to the high accumulation of dehydrocorydaline in the heart
- Preclinical Transplacental Transfer and Pharmacokinetics of Fipronil in Rats
- Detection of Weak Organic Anion-Transporting Polypeptide (OATP) 1B Inhibition by Probenecid (PROB) with Plasma-Based Coproporphyrin in Humans
- Quantification of Neonatal Fc Receptor (FcRn) and Beta-2 Microglobulin (β2M) in Human Liver Tissues by UPLC-MRM-Based Targeted Quantitative Proteomics for Applications in Biotherapeutic PBPK Models
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DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.
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Drug Metabolism and Disposition
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- Table of Contents (PDF)
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- Strain-Dependent Variability of Early Discovery Small Molecule Pharmacokinetics in Mice: Does Strain Matter?
- OATP1B3 Expression and Function is Modulated by Coexpression with OCT1, OATP1B1, and NTCP
- Urinary Bile Acid Profile of Newborns Born by Cesarean Section Is Characterized by Oxidative Metabolism of Primary Bile Acids: Limited Roles of Fetal-Specific CYP3A7 in Cholate Oxidations
- Most Read
- Complete Structural Elucidation of Gemfibrozil Metabolites by Crystalline Sponges
- Metabolism and Disposition of Volanesorsen across Species
- Physiology of the Neonatal Gastrointestinal System
- Liver Zonation Index of Transporters and Enzymes in Mice
- Pharmacokinetics and Disposition of Biologics
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